We first described our algorithm in January 2025 (preprint), and throughout most of 2025, we presented some additional results at various conferences, such as ASMS in June 2025 (methods description), MSACL in September 2025 (operational considerations), and HUPO in November 2025 (a Parkinson's biomarker project ). And in February 2026, we published in JPR our peer-reviewed paper in which, unlike in the preprint, we fully disclose all the algorithms used to achieve quantification of the ~75-95% of peptides in DIA-MS data files that are typically ignored.

For those most interested in the "how" — i.e., how we achieve the quantification of nearly all the peptides present in the DIA-MS data files — we strongly recommend the ACS paper. In particular, reading the figures may provide the most information in the least amount of time.

For those interested more interested in the "what or why" — what does the GH algorithm ultimately provide and why should I care — the Parkinson's biomarker project may be the most interesting.